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CureHHT
  • HHT
    • What is HHT
      • Signs and Symptoms
      • Medical Summary
      • History of HHT
      • FAQ
    • Diagnosis & Treatment
      • International HHT Guidelines
      • Diagnostic Criteria for HHT
      • Genetic Testing for HHT
      • Screening Guidelines
      • Treatment of HHT
      • Newly Diagnosed
      • Nosebleed Severity Score
    • Get Support
      • HHT Treatment Centers
      • My HHT Tracker App
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Drug Therapy

Drug Therapy

Drugs are approved in the U.S. by the Food and Drug Administration (FDA) for specific purposes to help guide medical practice.

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Related Resources

Bevacizumab (Avastin) Use In HHT

Policy Statement – 2020

Hereditary hemorrhagic telangiectasia (HHT, also known as OslerWeber-Rendu Syndrome) is a condition that is characterized by focal proliferation of blood vessels (vascular malformations) in multiple organs. Two of the most commonly affected organs in…

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Bevacizumab for treating HHT patients with severe hepatic involvement or refractory anemia

Scientific Literature – 2020

PLoS One. Authors: Carolina Vázquez, María Laura Gonzalez, Augusto Ferraris, Juan Carlos Bandi, and Marcelo Martín Serra. This article is available for public use and does not require purchase. Click to view the full article.

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The Science Behind the 2019 Scientific Conference (recorded)

Webinar – 2020

Philippe Marambaud, PhD and Andy White, MD discuss important advances in HHT research which were presented at the 2019 HHT International Scientific Conference in Puerto Rico. Learn about advancements in drug therapies for bleeding, screening and trea…

More
Orphanet-Journal-of-Rare-Diseases-Future-treatments-for-HHT

Future Treatments for Hereditary Hemorrhagic Telangiectasia

Scientific Literature – 2020

Orphanet Journal of Rare Diseases. Authors: Florian Robert, Agnès Desroches-Castan, Sabine Bailly, Sophie Dupuis-Girod and Jean-Jacques Feige. This article is available for public use and does not require purchase. Click to view the full article.

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Systemic bevacizumab for high-output cardiac failure in HHT: an international survey of HHT centers

Scientific Literature – 2019

Orphanet Journal of Rare Diseases. Authors: Hanny Al-Samkari, Hasan A. Albitar, Scott E. Olitsky, Marianne S. Clancy and Vivek N. Iyer. This article is available for public use and does not require purchase. Click to view the full article.

More

Systemic bevacizumab for the treatment of chronic bleeding in HHT

Scientific Literature – 2018

Journal of Internal Medicine. Authors: Al-Samkari, H., Kritharis, A., Rodriguez-Lopez, J.M., and Kuter, D.J. This article can be purchased directly from the publisher. Click to view the article description and purchase options.

More

Endoglin Interacts with VEGFR2 to Promote Angiogenesis

Scientific Literature – 2018

The FASEB Journal. Authors: Hongyu Tian, Jennifer J. Huang, Christelle Golzio, Xia Gao, Melissa Hector-Greene, Nicholas Katsanis, and Gerard C. Blobe. This article is available for public use and does not require purchase. Click to view the full arti…

More

Endoglin Interacts with VEGFR2 to Promote Angiogenesis

Scientific Literature – 2018

Angiogenesis is the physiologic process by which new blood vessels arise from pre-existing vessels. Endoglin, a TGF-β coreceptor predominantly expressed in endothelial cells, plays an important role in vascular development and tumor-associated angiog…

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HHT: Diagnosis and Management from the Hematologist’s Perspective

Scientific Literature – 2018

Haematologica. Authors: Athena Kritharis, Hanny Al-Samkari, and David J Kuter. This article is available for public use and does not require purchase. Click to view the full article.

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The Current Role of Bevacizumab in the Treatment of Hereditary Hemorrhagic Telangiectasia Related Bleeding

Scientific Literature – 2018

Mayo Clinic. Author: James R. Gossage, MD This article is available for public use and does not require purchase. Click to view the full article.

More

HHT Scientific Conference Summaries (recorded)

Webinar – 2018

  Drs. Hughes, Faughnan and Andrejecsk provide a first hand synopsis of the HHT science presented in Dubrovnik, Croatia where over 200 voices were heard from 23 countries. They reviewed the 12th HHT International Conference Executive Summary of…

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Abstracts – 12th HHT International Scientific Conference (2017)

Scientific Literature – 2017

Angiogenesis. This article can be purchased directly from the publisher. Click to view the article description and purchase options.

More

Executive Summary – 12th HHT International Scientific Conference (2017)

Scientific Literature – 2017

Angiogenesis. Authors: Jillian W. Andrejecsk, Anna E. Hosman, Luisa M. Botella, Claire L. Shovlin, Helen M. Arthur, Sophie Dupuis-Girod, Elisabetta Buscarini, Christopher C. W. Hughes, Franck Lebrin, Christine L. Mummery, Marco C. Post, and Johannes…

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Hazardous Natural Health Products in HHT

Article – 2017

HHT patients can bleed easily, which is why products that may thin your blood or reduce your ability to clot can be very dangerous. This handout was developed by Daniel Cortes, Pharmacist at the St. Michael’s Hospital HHT Center in Toronto, Canada, t…

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Effect of Bevacizumab Nasal Spray on Epistaxis Duration in HHT. A Randomized Clinical Trial

Scientific Literature – 2016

JAMA. Authors: Sophie Dupuis-Girod, PhD, Alexis Ambrun, MD, and Evelyne Decullier, PhD. This article is available for public use and does not require purchase. Click to view the full article.

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Related News

February 2, 2020

Recorded WEBINAR: The Science Behind the 2019 Scientific Conference

Now available!

Research, Medical, Access and Awareness Initiatives Brochure

Cure HHT – 2019 Research, Medical Access and Awareness Initiatives Brochure

December 17, 2019
Seed Money

HHT Scientific Advancement Through Federal Grants

December 10, 2019

Everyone Should Use Backpack Health!

September 4, 2019

2019 Scientific Conference Recap

August 26, 2019
Girl Bloody Nose Tissue

Stanford’s Avastin Study is Complete!

April 17, 2019
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