Drug Therapy
Drugs are approved in the U.S. by the Food and Drug Administration (FDA) for specific purposes to help guide medical practice.
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Endoglin Interacts with VEGFR2 to Promote Angiogenesis
Scientific Literature – 2018The FASEB Journal. Authors: Hongyu Tian, Jennifer J. Huang, Christelle Golzio, Xia Gao, Melissa Hector-Greene, Nicholas Katsanis, and Gerard C. Blobe. This article is available for public use and does not require purchase. Click to view the full arti…
MoreEndoglin Interacts with VEGFR2 to Promote Angiogenesis
Scientific Literature – 2018Angiogenesis is the physiologic process by which new blood vessels arise from pre-existing vessels. Endoglin, a TGF-β coreceptor predominantly expressed in endothelial cells, plays an important role in vascular development and tumor-associated angiog…
MoreHHT: Diagnosis and Management from the Hematologist’s Perspective
Scientific Literature – 2018Haematologica. Authors: Athena Kritharis, Hanny Al-Samkari, and David J Kuter. This article is available for public use and does not require purchase. Click to view the full article.
MoreThe Current Role of Bevacizumab in the Treatment of Hereditary Hemorrhagic Telangiectasia Related Bleeding
Scientific Literature – 2018Mayo Clinic. Author: James R. Gossage, MD This article is available for public use and does not require purchase. Click to view the full article.
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HHT Scientific Conference Summaries (recorded)
Webinar – 2018Drs. Hughes, Faughnan and Andrejecsk provide a first hand synopsis of the HHT science presented in Dubrovnik, Croatia where over 200 voices were heard from 23 countries. They reviewed the 12th HHT International Conference Executive Summary of…
MoreAbstracts – 12th HHT International Scientific Conference (2017)
Scientific Literature – 2017Angiogenesis. This article can be purchased directly from the publisher. Click to view the article description and purchase options.
MoreExecutive Summary – 12th HHT International Scientific Conference (2017)
Scientific Literature – 2017Angiogenesis. Authors: Jillian W. Andrejecsk, Anna E. Hosman, Luisa M. Botella, Claire L. Shovlin, Helen M. Arthur, Sophie Dupuis-Girod, Elisabetta Buscarini, Christopher C. W. Hughes, Franck Lebrin, Christine L. Mummery, Marco C. Post, and Johannes…
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Hazardous Natural Health Products in HHT
Article – 2017HHT patients can bleed easily, which is why products that may thin your blood or reduce your ability to clot can be very dangerous. This handout was developed by Daniel Cortes, Pharmacist at the St. Michael’s Hospital HHT Center in Toronto, Canada, t…
MoreEffect of Bevacizumab Nasal Spray on Epistaxis Duration in HHT. A Randomized Clinical Trial
Scientific Literature – 2016JAMA. Authors: Sophie Dupuis-Girod, PhD, Alexis Ambrun, MD, and Evelyne Decullier, PhD. This article is available for public use and does not require purchase. Click to view the full article.
MoreExecutive Summary – 11th HHT International Scientific Conference (2015)
Scientific Literature – 2015Angiogenesis. Authors: Helen Arthur, Urban Geisthoff, James R. Gossage, Christopher C. W. Hughes, Pascal Lacombe, Mary E. Meek, Paul Oh, Beth L Roman, Scott O. Trerotola, Sebastiaan Velthuis, and Whitney Wooderchak-Donahue. This article can be purcha…
MoreAbstracts – 11th HHT International Scientific Conference (2015)
Scientific Literature – 2015Angiogenesis. This article can be purchased directly from the publisher. Click to view the article description and purchase options.
MoreIntravenous Bevacizumab for Complications of HHT: A Review of Literature
Scientific Literature – 2015International Forum of Allergy & Rhinology. Authors: Natalia P. Arizmendez, Luke Rudmik, and David M. Poetker. This article can be purchased directly from the publisher. Click to view the article description and purchase options.
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Dose-Response Relationship of Bevacizumab in HHT
Scientific Literature – 2015Mabs. Authors: Nicolas Azzopardi, Sophie Dupuis-Girod, David Ternant, Anne-Emmanuelle Fargeton, Isabelle Ginon, Frédéric Faure, Evelyne Decullier, Adeline Roux, Marie-France Carette, Brigitte Gilbert-Dussardier, Pierre-Yves Hatron, Pascal Lacombe, Va…
MoreVEGF Neutralization can Prevent and Normalize Arteriovenous Malformations in an Animal Model for HHT2
Scientific Literature – 2014Angiogenesis. Authors: Chul Han, Se-Woon Choe, Yong Hwan Kim, Abhinav P. Acharya, Benjamin G. Keselowsky, Brian S. Sorg, Young-Jae Lee, and S. Paul Oh. This article is available for public use and does not require purchase. Click to view the full art…
MoreHereditary Hemorrhagic Telangiectasia: From Molecular Biology to Patient Care
Scientific Literature – 2010Journal of Thrombosis and Haemostasis. Authors: S. Dupuis-Girod, S. Bailly, and H. Plauchu. This article is available for public use and does not require purchase. Click to view the full article.
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