HHT: Diagnosis and Management from the Hematologist’s Perspective

This review discusses the biology of HHT, management issues that face the practising hematologist, and considerations of future directions in HHT treatment. The diagnosis of hereditary hemorrhagic telangiectasia is clinical, based on the Curaçao criteria. Genetic mutations that have been identified include ENG, ACVRL1/ALK1, and MADH4/SMAD4, among others.Optimal treatment is best delivered via a multidisciplinary approach with appropriate diagnosis, screening and local and/or systemic management of lesions. (view resource to learn more)