Pharmacokinetic-Pharmacodynamic Correlation from Mouse to Human with Pazopanib, a Multikinase Angiogenesis Inhibitor with Potent Antitumor and Antiangiogenic Activity

Molecular Cancer Therapeutics (2007); Authors: Rakesh Kumar, Victoria B. Knick, Sharon K. Rudolph, Jennifer H. Johnson, Renae M. Crosby, Ming-Chih Crouthamel, Teresa M. Hopper, Charles G. Miller, Laura E. Harrington, James A. Onori, Robert J. Mullin, Tona M. Gilmer, Anne T. Truesdale, Andrea H. Epperly, Amogh Boloor, Jeffrey A. Stafford, Deirdre K. Luttrell, and Mui Cheung