Research Projects Funded 2006

2006 HHT Research Grant Awards

Mechanism of Disease $50,000 Research Grand Award

Dr. Michelle Letarte, Toronto Hospital for Sick Children, for the project: TGF-B activates eNOS and regulates vasomotor function by an endoglin-and Alk-1' dependent mechanism.

Treatment of Disease $50,000 Research Grant Award

Professor Christine Mummery, Utrecht, The Netherlands, for the project: Differentiation of Eng-/- embryonic stem cells in embryoid bodies, a paradigm for vascuaogenesis/angiogenesis defects in HHT and a potential drug screen. Dr. Mummery will examine the effects of Thalidomide on blood vessel structure.